Bone pain is commonly caused by fractures due to trauma, rheumatoid arthritis, tuberculosis, etc. Medications should be administered to address the disease, and commonly used medications include non-steroidal anti-inflammatory drugs (NSAIDs), anti-rheumatic drugs, and anti-tuberculosis drugs. The commonly used therapeutic drugs are as follows: 1. Fractures caused by trauma: generally take non-steroidal anti-inflammatory drugs such as celecoxib and nimesulide for anti-inflammatory and pain relief after fixation and braking. 2. Rheumatoid arthritis: the bone pain caused by this kind of disease is usually treated with anti-rheumatic drugs such as methotrexate tablets and leflunomide. 3. Bone tuberculosis: Bone pain caused by such diseases is usually treated with anti-tuberculosis drugs such as isoniazid and rifampicin. There may be other causes of bone pain, such as osteomyelitis, osteomalacia, etc. It is recommended to take the corresponding medication for the treatment of the disease. The above drugs should be taken under the guidance of a professional physician and pharmacist.