Multiple breast nodules need to be determined according to the nature of the nodule, patient’s symptoms, and the size of the nodule to decide whether surgery is needed. It is recommended that the patient go to the hospital in time to clarify the cause of the disease and treat the cause. 1. Nature of nodules: Nodules can be categorized into benign and malignant. Benign nodules are generally breast hyperplasia or benign breast tumors, while malignant nodules are breast cancer. If diagnosed as breast cancer, surgery should be performed as soon as possible. The diagnosis of breast hyperplasia or benign breast tumor is based on follow-up examination. 2. Patient’s symptoms: If the patient has obvious breast pain, combined with nipple overflow and other symptoms, which affects normal life and work, surgical excision can be performed to relieve the symptoms. Surgical excision can be performed to relieve the symptoms. 3. Nodule size: If the nodule is caused by breast hyperplasia or benign breast tumor, regular follow-up and observation are usually the main concern, but if the diameter of the nodule is too large, resulting in the patient’s discomfort, surgical excision should be performed. Multiple breast nodules are mostly seen in breast hyperplasia or benign breast tumors, and breast cancer is usually a single tumor, so it is recommended to go to the hospital in time to improve the examination.