Blockage of the medial thigh meridians can cause pain or numbness in the medial thigh area, usually manifesting as radiating pain or pins-and-needles pain in the medial region. The most common clinical cause is due to muscle strain and inflammation of the fascia in the inner thigh, which results in pain, mainly manifested as localized soreness and swelling, which can be induced by walking activities and can be relieved when resting. For such cases, first of all, we should ensure sufficient rest, avoid strenuous exercise, and if necessary, we can cooperate with symptomatic treatment with drugs, otherwise chronic inflammatory reaction will easily occur, leaving chronic pain in the inner thigh area, which will be induced once strain or strenuous exercise. The second cause of pain may be caused by nerve compression, for this case should be clear about the site of compression, as soon as possible to lift the compression or eliminate the local inflammatory reaction, otherwise the nerve compression for a long time, there will be ischemic necrosis, which will lead to local muscle atrophy, difficult to move.