Immunotherapy for gastric cancer, also known as immunobiotherapy, refers to a promising treatment for gastric cancer in addition to surgery, chemotherapy and radiotherapy. It mainly stimulates or mobilizes the immune system of the body to enhance the anti-tumor immunity of the tumor microenvironment so as to inhibit and kill tumor cells, commonly used are non-specific immunosuppressants, cytokines and molecular targeted therapy, as follows: 1. Non-specific immunosuppressants: commonly used drugs such as yunzhi polysaccharide, thymidine and shiitake mushroom polysaccharide can promote the proliferation of mononuclear macrophages, enhance the activity of T cells, NK cells and the release of various cytokines, so as to achieve the goal of the treatment of gastric cancer. 2.Cytokine therapy: It is a kind of biological response regulator which is widely used and has clear efficacy, commonly used are interleukin-2, tumor necrosis factor, etc. 3.Molecular targeting therapy: Targeting the proto-oncogene products of tumor cells or their signaling pathways, key molecules, through monoclonal antibodies of anti-target molecules or These drugs have high selectivity to tumor cells and less toxic side effects.