The symptoms of liver not harboring the soul are mainly difficulty in sleeping, irritability and insomnia, and then the mental manifestations are anxiety, depression and lack of energy in doing things, as if there is no soul, which are the symptoms related to liver not harboring the soul. Clinically, it can be treated by some Chinese herbal formulas, such as Gentian and Liver Pill, Chaihu and Liver Dispersion, and Zhuangyao Pill, which can regulate human emotions and improve the flow of Qi, blood and fluids, and have a very good effect on the circulation of the liver, so that the liver does not harbor the soul can be effectively treated. The liver can also be regulated through exercise and diet, including qigong and yoga, all of which can improve the symptoms.