Not all patients with neocoronavirus infection will have sequelae after cure, and the more common sequelae include respiratory and circulatory sequelae, neurological sequelae, and sequelae related to psychological and cognitive disorders, etc. The most common sequelae are: decreased cardiopulmonary exercise tolerance is one of the most common symptoms in patients recovering from neocoronavirus infection. 1. Respiratory sequelae: Decreased cardiopulmonary exercise tolerance is one of the most common symptoms in patients recovering from neocoronaryngitis, and patients with severe acute infection may also have dyspnea and fatigue, which can be improved with the passage of time. In addition, abnormal diffusion capacity of pulmonary carbon dioxide diffusion volume and interstitial lung injury can also be seen. 2. Sequelae of the circulatory system: The new coronary pneumonia causes many cardiac complications, such as hypertension, arrhythmia, coronary atherosclerosis and heart failure, which are mainly related to virus-induced myocardial injury, hypoxia, and down-regulation of angiotensin-converting enzyme 2 receptor, and so on. 3. Neurological sequelae: they may be manifested as cognitive disorders such as decreased sense of smell, delirium, etc., postural tremor and mild motor/sensory deficits, etc., whose pathophysiological mechanisms have not been fully clarified. 4. Sequelae related to psychological and cognitive disorders: after discharge from the hospital, patients with neocoronaryngitis commonly suffer from emotional disturbances including anxiety, depression, fear, memory and attention loss, sleep disorders, cognitive disorders and other mental health problems, and in severe cases, even despair. Now the research about the sequelae of the new crown is still insufficient, it is recommended that we do a good job in our daily lives to protect against infection. Tip: The terms “new coronary pneumonia and new coronary virus pneumonia” mentioned in this article were renamed to “new coronary virus infection” on December 26, 2022, as announced by the National Health Commission.