Klüver-Bucy syndrome, which has been reported to occur in up to 70% of cases, is a behavioral abnormality related to temporal lobe function, similar to KBS in animals with bilateral temporal lobe removal. For example, visual awareness is not possible and the inability to recognize the face of a loved one or the self in a mirror. Exploring objects with the mouth (mouth exploration disorder), which can also manifest as compulsive chewing of gum or smoking, as well as stroking and touching objects in front of the eyes with the hands and excessive appetite and casual eating. In 1939 neuropathologists Klüver and Bucy made an experimental animal model of monkeys with resected bilateral temporal lobes, observed abnormal mental behavior changes in monkeys and described a set of symptoms that appeared in animals with bilateral temporal lobe deficits. It is called Klüver Bucy syndrome. In 1975, Marlowe et al. first reported the development of KBS in humans after herpes simplex virus encephalitis. Klüver-Bucy syndrome is associated with bilateral temporal lobe injury and is most closely related to bilateral temporal pole and medial temporal lobe lesions in particular. There are extensive associations between the temporal lobes and other sites, such as altered sexual behavior, calm emotional indifference, and hyperacuity to visual stimuli associated with hypothalamic and bilateral amygdala lesions. For example, there are abnormal sexual activities such as bulimia, hyperacuity to visual stimuli, and preference for exposing private parts. Exploration of objects with the mouth (oral exploration disorder) is seen in Alzheimer’s disease dementia. Alzheimer’s disease dementia used to be referred to as progeria for those with onset before the age of 65 and senile dementia for those with onset after the age of 65.