Neck wrinkles are naturally occurring fine lines on the neck, which can deepen with age or exposure to wind and sun. The deepening of neck wrinkles and skin laxity are also one of the signs of aging, especially for those who had a swan-like white and long neck when they were young, but with the changes of the years, it is no less disturbing than the aging of the facial features. Neck slowly appeared fine lines, skin gradually sagging, jaw and neck of the smooth contour is no longer there. Many people focus on facial maintenance, nutritional milk, sunscreen, do not pay attention to the neck maintenance, and let the neck exposed age. Platelet-rich plasma (PRP) refers to the extraction of the patient’s own whole blood, centrifugation, removal of red blood cells, white fine run, to obtain platelet-rich plasma, activation and release of a variety of autologous growth factors, such as platelet-derived growth factor PDGF, Epidermal Growth Factor EGF, Vascular Endothelial Growth Factor VEGF, Transforming Growth Factor TGF and Fibroblast Growth Factor FGF. and fibroblast growth factor FGF, which can stimulate cell proliferation, increase collagen synthesis, and stimulate the formation of neovascularization, and promote the proliferation and differentiation of stem cells, so it can be used for facial rejuvenation, injection of periorbital skin, to reduce crow’s feet, injection of the neck, to remove the neck lines. Apply RegebLabkit to draw 8ml of patient’s blood, prepare 2ml of PRP, inject to treat crow’s feet and neck lines. Advantages: easy, autologous, less invasive, can be injected repeatedly, can be used for anti-aging or improving skin quality.