Rett’s syndrome has a wide range of manifestations, mostly characterized by slow growth, mental retardation, and movement disorders as the child grows and develops. Rett syndrome is a mental developmental disorder, a genetic variant located on the X chromosome that causes severe mental retardation. Patients with Rett syndrome show no abnormalities during the perinatal period, but at 6 to 8 months of age, they have developmental arrest, developmental regression, reduced intellectual and social abilities, and symptoms such as rubbing, licking, clapping, or grasping hair and clothing with their hands. They gradually lose the ability to use their hands in a planned manner, and have reduced walking ability, and decreased or even loss of language skills. If Rett’s syndrome is suspected, it is recommended to go to the hospital as soon as possible and under the guidance of a doctor to undergo the relevant examinations to clarify the disease and treat it appropriately.