For hormone drugs need to standardize the use of hormones, including the amount of hormones, the course of treatment, all need to use standardized. Halometasone can produce the following harms if used irregularly for a long time: 1, inhibit the synthesis of stratum corneum lipids, so that the skin barrier is damaged and the skin is dry.2, inhibit the proliferation of the epidermis as well as differentiation, the skin thins and atrophies.3, it can make the skin easy to flake off, mainly because of its reduction of the adhesion between the keratinocytes.4, increase the tone of blood vessels, resulting in capillary dilatation and the emergence of redness.5, hormone There is an immunosuppressive effect, which will increase the possibility of local infection, leading to the occurrence of folliculitis and the aggravation of acne. So for the application of halometasone, it should be standardized.