Gentamicin can be administered as an enema using 16 to 240,000 units. Gentamicin, an aminoglycoside antibiotic, can play an antibacterial role by binding to the 30S subunit of the bacterial ribosome and blocking bacterial protein synthesis. Clinically, it is mainly used to relieve symptoms of infections caused by sensitive bacteria, especially those caused by gram-negative bacteria. Oral administration is suitable for the treatment of bacterial dysentery and other bacterial intestinal infections, can also be used for the preparation of colon surgery, can also be used for the treatment of chronic gastritis, can be used in conjunction with anti-ulcer drugs (such as omeprazole, ranitidine, etc.) for the treatment of peptic ulcer caused by Helicobacter pylori infection. It can be administered by enema for the treatment of ulcerative colitis. Urine routine and renal function should be measured before using gentamicin. Prior to administration, it is necessary to ascertain whether the patient is using drugs that are ototoxic, nephrotoxic, or aggravate neuromuscular blockade, such as isoniazid, and whether there is a history of allergy to gentamicin or other aminoglycosides. Gentamicin should be used under the guidance of a physician and should not be used without authorization.