Indicators of systemic lupus erythematosus suggesting improvement of the condition include blood sedimentation, complement, antinuclear antibody, urine protein, blood routine, and so on. SLE is an autoimmune connective tissue disease, and symptoms such as redness and swelling of joints, joint pain, skin rashes, weight loss, fever, etc. will gradually be relieved when the condition of patients with the disease improves. In addition, laboratory indexes such as blood sedimentation, complement, antinuclear antibody, urinary proteins, blood routine, etc. also provide important references for judging the activity of SLE. In addition, echocardiography, funduscopic examination, right heart catheterization and other auxiliary examinations can also help to understand the involvement of the heart, lungs and eyes, and whether the patient has improved after treatment. The condition of SLE patients should be analyzed by specialists with rich experience in diagnosis and treatment, and it is recommended that patients go to the Department of Rheumatology and Immunology of regular hospitals for detailed consultation and treatment according to the doctor’s instructions.