Low progesterone is not associated with men; low progesterone may be related to luteal insufficiency, endocrine dysfunction and other causes. Progesterone is a kind of progesterone secreted by the ovarian corpus luteum, which has the role of maintaining pregnancy and regulating menstruation. The amount of progesterone secreted does not have any relationship with men, so low progesterone levels are not related to men. Common clinical causes of low progesterone include physiologic and pathologic. Physiologic low progesterone is commonly seen in early pregnancy, when low progesterone can occur due to the pulsatile release of progesterone. Pathological low progesterone is seen in women with luteal insufficiency and endocrine dysfunction, the ovarian corpus luteum secretes insufficient amounts of progesterone, which can also be low. It is recommended that people with low progesterone consult a doctor in time to clarify the cause of the disease and actively receive treatment.