The high percentage of clot ablation indicates hyperfibrinolysis, which is categorized into primary and secondary hyperfibrinolysis according to the etiology, and its treatments include primary pathogenesis treatment, drug treatment, and so on. 1. Primary hyperfibrinolysis: it is due to various reasons such as congenital deficiency of fibrinogen activator inhibitor-1, increase of fibrinogen activator, severe liver disease, tumor, trauma, etc., which leads to the large amount of degradation of coagulation factors and cause bleeding, and its treatment mainly includes the treatment of the primary pathology, such as the treatment of severe liver disease, tumor, etc., and the treatment of fibrinolysis inhibitor such as aminocaproic acid and tranexamic acid. 2. Secondary hyperfibrinolysis: it refers to hyperfibrinolysis secondary to intravascular coagulation, mainly seen in disseminated intravascular coagulation, thrombotic diseases, etc. Its main treatment modalities are fresh frozen plasma, antifibrinolytic drugs such as aminocaproic acid, tranexamic acid and so on. Patients with hyperfibrinolysis should go to the hospital for further examination and medication under the guidance of a professional doctor.