Is moderately differentiated colon cancer pT3N0M0 stage IIA?



Pathological examination of moderately differentiated colon cancer pT3N0M0 is stage IIA, which is feasible to be treated by surgical resection, and single-agent chemotherapy and other treatments are selected according to the presence of risk factors.

Pathological examination of moderately differentiated colon cancer shows that the tumor penetrates the intrinsic muscular layer and invades the peri-intestinal tissues without lymph node metastasis and distant metastasis, which is evaluated as pT3N0M0 and staged as stage IIA. Tumors in this stage may present with blood in stool, diarrhea, abdominal pain and other manifestations, and may present with intestinal obstruction.

For tumors in this stage, if they can be resected, they need to be surgically removed as soon as possible. If there are cases of poor histological differentiation of the tumor, tumor invasion of peripheral blood vessels or lymphatic vessels, tumor invasion of nerves, preoperative intestinal obstruction, tumor perforation, etc., it is necessary to carry out fluorouracil single-agent chemotherapy, or oxaliplatin-based combination chemotherapy regimen, etc., after surgery.

The above drugs need to be used under the guidance of clinicians, and unauthorized use of drugs is prohibited; if the disease is diagnosed, it is recommended to go to the hospital in time.