Pus coming out of a pustule from a nail trim is usually due to an aggravation of the soft tissue infection around the nail, which has become pus-filled. It can be treated by incision and drainage, medication, and removal of the finger (toe) nail. 1. Incision and drainage: If there is pus in the nail groin infection, first of all, we need to thoroughly disinfect the epidermis of the pus, and incise and drain the pus. If necessary, you can also put oil gauze to drain. 2. medication: inguinitis needs to be treated with antibiotics, such as oral amoxicillin capsules and cefixime tablets. You can also apply mupirocin ointment and other drugs for treatment. 3. Remove the finger (toe) nail: after the emergence of pus in the nail groin infection, if the symptoms are serious. Surgical incision of the fingernail or removal of the fingernail (toenail) for treatment is needed to completely remove the pus, so that inguinitis can be well treated. It is recommended that patients go to the hospital in time and follow the doctor’s instructions for standardized treatment. In addition, the use of drugs must be under the guidance of a doctor.