The location of the liver is mainly in the right upper abdominal quaternary region. The liver is the largest gland in the human body, divided into left and right lobes, wedge-shaped, with a large head on the right and a small head on the left, with a large volume and weight, most of which is located in the right upper abdominal quaternary region, and a small portion of the tip of the liver probes into the left upper abdominal quaternary region. Because of the large area and the lack of overall bony surface protection, it is easy to be damaged and ruptured by violent blows. Most of the front part of the liver is covered by ribs, the upper edge is located in the 5th intercostal space, the lower edge is basically in the right costal arch edge, a small part is located in the left and right intercostal arch, about 3cm below the sternal raphe, and then the left part is covered by the left costal arch. Normal examination of the liver is generally not easily palpable except in pediatric patients. Above the liver is the diaphragm, with ligaments connecting it to the lower part, which can move up and down with the diaphragm lightly by 2-3cm when breathing, and when standing, the liver will drop a little bit due to its own gravity compared with when lying down, so the position of the liver is not completely fixed. The right adrenal gland and the right kidney are at the back of the liver, and the left lobe is near the esophagus; the right lobe of the liver is adjacent to the right curvature of the colon, the middle part of the liver is adjacent to the upper part of the duodenum under the hepatic portal, and the left lobe of the liver is adjacent to the stomach. The main functions of the liver are bile secretion, digestion and metabolism, coagulation and hemostasis, and detoxification. Inflammation, tumor, etc. can cause pain or pressure pain in the liver area, and liver enlargement or mass can be detected on examination, which requires timely medical consultation.