Naltrexone has national approval. Naltrexone is used as an adjunctive medication to prevent relapse after detoxification of opioid-dependent individuals and has been approved by the State Food and Drug Administration. The main adverse reactions of naltrexone are gastrointestinal discomfort, such as nausea and vomiting, poor appetite, abdominal pain and diarrhea; dizziness and headache, fatigue, rash, sleep disorders, anxiety, and other symptoms, which will be gradually reduced or disappeared with the prolongation of the duration of the drug. In addition, taking Naltrexone can also lead to liver function abnormalities, such as increased transaminases, so the liver function should be checked regularly during the use of the drug. Naltrexone is mainly contraindicated for people who are allergic to this drug; are applying medical drugs containing opioids with opioid dependence, positive naloxone provocation test or positive urine morphine test; people with acute hepatitis or poor liver function. Taking naltrexone needs to be taken under the guidance of a professional doctor to avoid adverse consequences.