The patient doesn’t want to eat and still has nausea and vomiting, it needs to depend on the time of the onset of the patient’s illness and whether or not he or she has gas and bowel movements. If it appears in the last 2-3 days, preceded by alcohol consumption and stopping gas and defecation, it is likely to be caused by pyloric duct obstruction and ulceration, which needs to be clarified by taking a standing plain film of the abdomen or doing an electronic gastroscopy. If the patient has the above symptoms, along with diarrhea, abdominal pain and other symptoms, is likely to be acute gastroenteritis, in acute gastroenteritis caused by diarrhea will lead to low potassium, manifested by nausea and want to vomit, can be clarified through the blood sampling and examination of ion biochemistry, blood routine and stool routine tests. After the diagnosis is confirmed, anti-infection, potassium, sodium and other plasma treatment is needed. If the patient has this symptom for a long time, but there is gas, defecation, but also to exclude the possibility of functional gastropathy or pancreatic achalasia, need to do barium meal examination of the upper gastrointestinal tract to clarify the diagnosis of esophageal dilatation or pancreatic surgery treatment.