The majority of female reproductive tract anomalies are found in patients with uterine anomalies, which are one of the more common causes of female health and reproductive function. The prevalence of uterine malformations has been reported to be 5.5% in the general population and about 8% in infertile patients. Fortunately, most patients with uterine anomalies can have normal pregnancies and deliveries, but there are still some patients with uterine anomalies who have combined infertility factors and need to resort to assisted reproductive treatment. It is also important to note that both domestic and foreign studies have shown that in patients with uterine anomalies combined with infertility, the outcome of assisted reproductive technology is worse than in infertility patients with normal uterus, and the possibility of abnormalities throughout the pregnancy increases, even threatening the life of the mother and child. Therefore, it should be clarified that pure uterine anomalies are not an indication for assisted reproductive treatment, but only patients with uterine anomalies combined with infertility need assisted reproductive treatment. Only patients with uterine anomalies combined with infertility need to undergo assisted reproductive treatment, and they need to work with a professional assisted reproductive physician to select the appropriate techniques and procedures. In addition, patients themselves should have reasonable expectations of assisted conception and pregnancy outcome, as it is destined to be difficult for patients with uterine anomalies combined with infertility to obtain a lovely baby. The fertility outcome of the patient is influenced by the type of uterine malformation. Overall, the higher incidence of primary infertility is found in primordial uterus, infantile uterus, and congenital absence of vagina, the higher to lower incidence of miscarriage is found in longitudinal uterus, bicornuate uterus, unicornuate uterus, and bicornuate uterus, and the higher to lower chance of successful delivery is found in bicornuate uterus, unicornuate uterus, and bicornuate uterus. Although most patients with uterine anomalies combined with infertility can seek help from assisted reproduction, some severe types of uterine anomalies such as severe primordial uterus, even though the ovaries are normal and theoretically a suitable fertilized egg can be obtained, pregnancy outcome is difficult to improve due to the lack of suitable soil. Therefore, whether to perform uterine orthopedics and what assisted reproductive techniques to perform in patients with various types of malformed uterus combined with infertility need to be carefully studied and explored. Moreover, for the special group of patients with uterine anomalies, adequate evaluation before assisted conception, appropriate choice of correction, rational use of assisted reproductive techniques, as well as health care during pregnancy and special management of delivery are essential. In conclusion, most patients with uterine anomalies do not require assisted reproduction techniques, and only some patients with uterine anomalies combined with infertility require IVF, and the specific fertility outcome is influenced by the type of uterine anomaly and other infertility factors.