The normal value of γ-glutamyl transpeptidase is usually below 50U/L. The test value of 311U/L is obviously higher than normal value, which suggests that there may be biliary obstruction, drug-induced hepatitis, hepatocellular carcinoma, etc. However, this is only a test indicator, which can not tell the severity of the disease clearly, and it should be combined with the comprehensive judgment of blood tests.
1. Biliary obstruction: biliary obstruction such as biliary cirrhosis, cholangitis, etc., which leads to γ-glutamyl transpeptidase excretion obstruction, may appear γ-glutamyl transpeptidase 311 U/L. If there is no other complication, timely treatment can alleviate the condition, and it will not be too serious.
2. Pharmacologic hepatitis: taking acetaminophen and statin drugs causes pharmacologic liver injury, the function of hepatocytes decreases, and glutamyl transpeptidase cannot be excreted normally, and the phenomenon may also occur. Stopping or changing drugs in time will not be very serious and can effectively improve the condition.
3. Hepatocellular carcinoma: Due to tumor proliferation, patients with hepatocellular carcinoma have abnormal excretion of γ-glutamyl transpeptidase, and at the same time, the cancer cells will also produce the substance, which will result in significantly elevated test value. Measurement of alpha-fetoprotein and pathological tissue biopsy can also be carried out to clarify the diagnosis. This condition is usually serious and should be treated promptly.
When this test result occurs, relevant examinations should be carried out promptly under the guidance of a doctor to identify the cause and provide reasonable treatment to avoid delaying the condition.