Zinc phosphide is a common rodenticide, and most human poisonings are caused by accidental or suicidal ingestion, with digestive and neurological symptoms. Gastrointestinal symptoms include nausea, vomiting, abdominal pain, and difficulty breathing. Nervous system symptoms mainly appear coma, convulsions, heavy can appear respiratory and circulatory failure, eventually lead to death. It is very important that patients with zinc phosphide poisoning come to the emergency room as soon as possible because emesis, gastric lavage, or diarrhea within 6 hours of acute poisoning will reduce the absorption of the toxin and thus alleviate the symptoms. In zinc phosphide poisoning, rehydration and diuretic therapy are given. If symptoms are severe, it may be treated with blood purification. In the course of treatment, the patient’s clinical symptoms are actively observed to see if serious complications such as pulmonary edema and cerebral edema occur, and if they do, they will be admitted to the intensive care unit for treatment.