Jagged edges of the tongue accompanied by pain may be caused by malocclusion, inflammation of the tongue or tumors, which should be treated with dental treatment, medication or surgery. 1. Malocclusion. Jagged edges of the tongue with pain may be caused by excessive protrusion of denture restoration or the existence of bad jaw curves, which will easily bite the lateral edge of the tongue when biting up and down, resulting in tongue injury and pain. The treatment generally needs to restore the normal jaw curve, establish the normal overjaw coverage relationship, and trim the denture excessive convexity. 2. Inflammation of the tongue. When there is tongue amyloidosis, it will be manifested as progressive megaglossia, teeth marks on both sides of the tongue, and pain in the tongue, and the treatment is usually symptomatic with drugs such as Prednisolone or melphalan. 3. Tumor of tongue body. When there is a tumor in the tongue tissue, it will lead to the enlargement of the tongue body, and the tumor grows progressively, which can compress and invade the nerves and cause pain, and it needs to be surgically removed according to the situation. Any discomfort in the oral cavity, it is recommended to go to the hospital in time to avoid damage to health, and the medication should be prescribed by the doctor.