It is difficult to sleep at night with sore and swollen calves, which is mainly considered to be related to overwork during the day, cold, calcium deficiency, local inflammation or lumbar spine pathology. 1. Overwork during the day: a lot of sports or heavy physical activities during the day will easily lead to calf muscle fatigue and excessive secretion of lactic acid locally, which will make it difficult to fall asleep at night. 2. Cold: the temperature is relatively low at night when you sleep, if the calf area is cold, it can affect the local blood circulation, thus producing the phenomenon of calf soreness and swelling and hard to fall asleep. 3. Calcium deficiency: If the intake of calcium is insufficient, or the calcium loss increases with age, it is easy to trigger the problem of osteoporosis, which will produce the symptom of soreness and swelling of the calves at night, and it is difficult to sleep, and there are even cramps in the calves. 4. Local inflammation: If inflammation occurs in the calf area, such as fasciitis, the stimulation of inflammation leads to an increase in inflammatory exudate, which can easily trigger the symptoms of soreness and swelling of the calves, affecting the quality of sleep. 5. Lumbar spine lesions: For patients with lumbar spine lesions, such as lumbar disc herniation or lumbar spinal stenosis, it is possible to compress the nerve roots, thus affecting the motor and sensory functions of the lower limbs, and it is difficult to fall asleep at night with soreness and swelling of the calves. If the symptoms are more serious, you need to seek medical examination as soon as possible, and standardized treatment under the guidance of a professional physician to prevent the aggravation of the condition at a later stage.