Jaundice of 11mg/dl at 43 days of age in infants is high and can be seen in infectious diseases, breast milk jaundice, congenital hypothyroidism. Intervention depends on the cause, such as cytomegalovirus infection, need to use ganciclovir and other treatment. 1. Infectious diseases: for example, cytomegalovirus infection, clinical yellowing of the skin may be present, and there may also be liver function impairment, hepatosplenomegaly, etc.. These babies need to be treated with antiviral drugs such as ganciclovir. 2. Breastfeeding jaundice: it refers to breastfed babies who still have jaundice 1~3 months after birth, which is manifested by elevated serum unconjugated bilirubin, except for other diseases. Generally, no treatment is needed and breastfeeding can be continued; when jaundice is greater than 15mg/dl, breastfeeding can be suspended under the guidance of a physician as appropriate, and jaundice can be significantly reduced after 72h. 3. Congenital hypothyroidism: this disease can affect the uptake and transportation of bilirubin in the liver, affecting the metabolism of bilirubin, and jaundice will not subside. For this kind of babies, thyroxine should be used for treatment under the guidance of physicians. 4. Other: In gastrointestinal surgical diseases, such as biliary atresia, the above phenomenon also occurs, and these babies need active surgical treatment to relieve the biliary obstruction. The above phenomenon can be seen in a variety of circumstances, it is recommended to actively consult the doctor, with the help of the doctor to identify the cause of the disease, and to carry out targeted treatment or therapy. All of the above medications should be used under the guidance of a doctor, and avoid self-medication.