For high homocysteine, mainly oral folic acid and vitamin B12 and methylcobalamin tablets are taken. Not only is high homocysteine a very important risk factor for cerebrovascular disease, but hyperhomocysteinemia also causes an increase in blood pressure at night or in the afternoon. Taking antihypertensive drugs alone may not have a good effect on lowering blood pressure, and only with folic acid, methylcobalamin or vitamin B12 tablets can blood pressure be well controlled. After treatment, regular review is needed to lower homocysteine to below the normal range, otherwise there is a high chance of getting cardiovascular disease, which includes risk factors such as smoking, alcohol, hyperlipidemia or hyperhomocysteine and hyperuricemia. Currently, there are more and more people with hyperhomocysteinemia, so when you go to the hospital for general checkups, you should include this item as a routine test.