There is no such thing as a high urine specific gravity making urine protein positive, but elevated urine specific gravity and urine protein can co-exist. It can be caused by physiologic factors such as low fluid intake, which concentrates the urine; it can also be caused by pathologic factors such as acute glomerulonephritis and diabetes mellitus. Physiological conditions such as diarrhea and low fluid intake can lead to inadequate renal perfusion, resulting in elevated urine specific gravity and urine protein, which requires fluid supplementation and regular review. Pathological factors such as acute glomerulonephritis, diabetes mellitus, etc., the glomerular filtration membrane is damaged, the urine contains more protein or glucose, etc., which can also be manifested as positive urine specific gravity and urine protein. Patients with abnormal urine specific gravity and urine protein are recommended to consult regular hospitals and receive standardized treatment under the guidance of physicians.