Clinical manifestations of disseminated intravascular coagulation

The clinical manifestations of disseminated intravascular coagulation mainly depend on the pathological and physiological basis of the patient, and the typical symptoms are as follows: 1, bleeding: can be manifested as multi-site bleeding, often predicting acute DIC, with skin purpura, petechiae and blood oozing from puncture sites or injection sites being more common, and constant blood oozing and blood non-coagulation from wound sites during and after surgery; 2, thromboembolism: due to thrombosis within small arteries, capillaries or small veins, the cause microthrombosis in various organs, resulting in underperfusion, ischemia or necrosis of organs, manifesting hemorrhagic purple spots at the end of the skin, gangrene of fingers or toes; 3, shock: the underlying disease of DIC and the DIC disease itself can induce shock; 4, impaired function of various organs: important organs such as the kidneys are damaged at a rate of 25%-67%, which can manifest as hematuria, oliguria or even anuria, central nervous system dysfunction It can be manifested as altered consciousness, convulsions or coma. Respiratory function is affected, manifesting as pulmonary hemorrhage and different degrees of hypoxemia. Gastrointestinal manifestations, which can be such as gastrointestinal bleeding. Liver dysfunction occurs in 22%-57% of cases and manifests as jaundice and liver failure. Diffuse intravascular coagulation is therefore a very serious state and once diagnosed urgent measures should be taken to correct circulatory disturbances and bleeding.