Glimepiride belongs to the sulfonylurea class of hypoglycemic drugs, the main role is to promote the secretion of insulin, and different from other sulfonylureas is that glimepiride has improved insulin sensitivity, so it is more suitable for patients with type 2 diabetes islet function is still partially preserved. And the duration of action of the drug is relatively long, if patients with high postprandial glucose can take one tablet orally in the morning, and if patients with high fasting glucose can take one tablet orally at night, both will have a better therapeutic effect. In general, Glimepiride is a very suitable glucose-lowering drug for type 2 diabetic patients, but there are prerequisites for taking Glimepiride orally, type 2 diabetic patients should have certain islet function, if insulin is obviously lacking it is not recommended to use Glimepiride, of course, type 1 diabetic patients can not take Glimepiride orally.