Vaccination is a powerful safeguard measure to improve children’s immunity and resist infectious diseases, and the healthy growth of babies cannot be achieved without timely vaccination. However, in recent years, there have been reports of serious adverse reactions in infants after vaccination, which has caused a lot of confusion to new mothers and fathers as to whether or not they should vaccinate their babies. First, parents should understand the principle of vaccination. Vaccination is the use of artificial methods to kill certain infectious bacteria and viruses or to reduce their toxicity by special methods to make vaccines, which are inoculated into the baby’s body in relatively safe doses by different methods and routes. It is equivalent to a minor bacterial or viral infection that forces the baby’s body to develop resistance to these bacteria or viruses, which reduces the possibility of the baby developing the disease when it encounters the same kind of bacteria or viruses again. It is important to emphasize that a vaccination can only be targeted against one infectious disease. Therefore, parents should pay great attention to the need for multiple vaccinations at different ages. So, what are the situations in which babies should not receive vaccinations? 1. Vaccines should be used with caution for those with allergies. Those who have a clear history of allergy to certain components of vaccines, or a history of allergy to certain vaccines in the past, should be prohibited from using the same vaccine. 2. Vaccination of patients with malignant tumors, those undergoing immunosuppressive therapy or those with other immune function defects can lead to serious consequences. It takes 4 weeks after gammaglobulin injection to receive measles vaccine. 3.Patients who are suffering from infectious diseases, or recovering from infectious diseases, or have a history of contact with acute infectious diseases such as measles or chickenpox and have not passed the observation period; those who have had close contact with tuberculosis patients or have a strong positive tuberculin test should not be vaccinated with BCG. 4. If you have various symptoms, such as fever, diarrhea, cough, vomiting, etc., vaccination may aggravate the original disease and may also aggravate the vaccine reaction, so you should suspend vaccination and wait until the baby has recovered from the disease. 5. Babies suffering from serious chronic diseases such as heart disease, liver disease, kidney disease, diabetes, active tuberculosis, blood system disorders, and active rheumatism should not be vaccinated. The vaccination should be carried out after the disease has returned to normal for more than six months. 6. Severe malnutrition, especially for infants under 1 year old with severe malnutrition, digestive disorders or disorders, should delay vaccination. 7.People suffering from neurological diseases, such as epilepsy, sequelae of encephalitis, history of high fever and convulsions, or people with past medical history should be cautious when receiving vaccination, especially when receiving vaccination against encephalitis B, mixed vaccine and rheumatoid polysaccharide vaccine. 8. Babies suffering from local skin infections, severe dermatitis, psoriasis, eczema and other diseases should not be vaccinated and should only be vaccinated after the skin disease has healed. Therefore, before vaccination, parents should take the initiative to introduce their baby’s health condition, previous vaccination history, and any allergy history to the doctor, and it is best to bring relevant medical history information, including some cases where it is difficult to judge whether the vaccination is suitable or not, and must tell the doctor to fully ensure the safety of vaccination.