Amoxicillin for headache usually does not work. There are many causes of headache, and the common types of headache are migraine, tension headache, cervicogenic headache, cluster headache, and none of the above common types of headache are related to internal infection. In the case of tension headache, it is often necessary to take Myna. Migraine headaches require ibuprofen, and cervicogenic headaches require medications such as pregabalin and gabapentin. There are also other types of headaches, such as hypertensive headaches, which require antihypertensive medication, and cluster headaches, which require hormones or oxygen. There are also headaches caused by intracranial infections, such as bacterial meningitis, where amoxicillin usually does not work and intravenous cephalosporin antibiotics are usually useful.