Taking rabeprazole is possible to cause body weakness, but clinically this adverse reaction is not common. Rabeprazole is a proton pump inhibitor, can inhibit gastric acid secretion, clinically commonly used in gastric ulcers, reflux esophagitis, duodenal ulcers and other diseases; allergic to rabeprazole, benzimidazole substitutes, pregnancy and breastfeeding women and other people should not take the drug treatment. After taking the drug there may be an adverse reaction of weakness in the limbs, so taking rabeprazole is likely to cause weakness. Apart from this, the adverse effects of rabeprazole include headache, nausea, bloating, abdominal pain, rash, flatulence, skin rash, itching, and feeling numb. Patients who need to take rabeprazole for treatment should use the drug under the guidance of a doctor, and it is recommended to visit a doctor if the adverse reactions are more serious after taking the drug.