Helicobacter pylori (Hp for short) is a spiral-shaped, microaerobic bacterium that requires very demanding growth conditions. It was first isolated in 1983 by the Australian scholar Barry? Marshall first successfully isolated it from gastric mucosal biopsy tissue of patients with chronic gastritis. On October 3, 2005, Australian gastroenterology clinician Barry Marshall and pathologist Robin K. Marshall and pathologist Robin Warren proposed that H. pylori should be isolated from the stomach. Warren won the 2005 Nobel Prize in Physiology and Medicine for proposing the etiological theory that H. pylori is associated with the development of gastritis and peptic ulcers, and further validating that long-term peptic ulcers lead to cancer. Unfortunately, this little story has been taken out of context by some of our countrymen, and has been misrepresented as being the cause of ulcer disease or cancer once infected by H. pylori, resulting in many years of talk of “bacteria”. Is H. pylori really that terrible? Not all people infected with H. pylori must be treated, in other words, it is not necessary to “kill” H. pylori. Why is that? Let’s talk about bacteria first. From the moment we are born and leave our mother’s body, we come into close contact with our natural environment, which is rich in microorganisms, so that the human body is host to tens of thousands of different microorganisms on the skin of the body and in the mucous membranes and cavities of the oral cavity, upper respiratory tract, intestinal tract, and genitourinary tract. The vast majority of these microorganisms are beneficial bacteria, which are beneficial to the human body, and it is these beneficial bacteria that maintain our health. These parasitic bacteria in our body, under normal circumstances and host peace, adapt to each other, help each other, a variety of microorganisms also restrain each other and maintain a state of mutual coexistence. It is impossible for any organism in nature to have even one microbial cell in the body. The normal flora and the host, and the normal flora maintain a good balance of survival through nutritional competition and mutual restraint of metabolites. What we call Helicobacter pylori belongs to one of their species. If this balance is broken under certain conditions, the normal parasitic bacteria that were not pathogenic may become pathogenic, and this kind of bacteria that make people sick under certain conditions we call opportunistic pathogens, also called conditional pathogens. In most cases, H. pylori will only come out when the body’s resistance is weakened. To use a common saying, “Hp (Helicobacter pylori) is like a spring, it is weak when you are strong and strong when you are weak”. There are countless opportunistic pathogens like H. pylori that cannot be killed by “sterilizing” them with antibiotics. The actual fact is that, if you have to be a good deal more than just a few days, you’ll be able to get a good deal more than just a few days. It is also common to see antibiotic-associated diarrhea caused by dysbiosis of the intestinal flora as a result of over-application of antibiotics. Therefore, the use of antibiotics to kill H. pylori in people with no clinical symptoms can do more harm than good.