Redness, dryness, peeling and pain on the sides of the nose may be due to contact dermatitis or rosacea, among other causes. It can be treated by applying the right medication according to the different conditions. 1. Contact dermatitis: redness, dryness, peeling and pain on both sides of the nose can occur after contact with certain allergic or irritating substances. Topical anti-inflammatory creams, such as Denuded cream, mometasone furoate cream and other medications, can be applied topically to the area of contact dermatitis. 2. Rosacea: related to heredity, skin barrier damage, vascular nerve dysfunction and other factors, can lead to continuous expansion of capillaries, thus causing redness on both sides of the nose, but also dry skin peeling pain symptoms. It can be treated with drugs such as brimonidine tartrate and azelaic acid. If the above symptoms occur, it is recommended to go to the hospital in a timely manner, under the guidance of the physician to carry out regular treatment. Do not blindly self-medication, in order to avoid adverse effects.