The difference between non-invasive DNA-plus and non-invasive DNA is mainly that non-invasive DNA-plus has a wider range of tests, although it is also a bit more expensive. Scope of testing: Non-invasive DNA mainly screens for common fetal chromosome number abnormalities, including Down’s syndrome, Edward’s syndrome, and Patau’s syndrome. Non-invasive PLUS, on the other hand, in addition to screening for the above conditions, can also screen for common chromosome micro-duplications and micro-deletions, and can screen for more than 10 types of fetal chromosomal disorders at one time. 2. Price: Non-invasive PLUS is more expensive than non-invasive DNA, and the specific price varies from hospital to hospital. Pregnant women are advised to consult their local regular hospitals and choose the appropriate screening program. Whether it is non-invasive DNA or non-invasive PLUS, if the screening result is high risk, the result cannot be used as a basis for diagnosis, and further amniocentesis is needed to make a clear diagnosis.