The “Iron Lady” and cerebrovascular dementia

  In May 1979, Margaret Thatcher became the first female prime minister in British history, and served three terms of 11 years. During her administration, she was known as the “Iron Lady” of the United Kingdom for her toughness and toughness in both internal and external affairs.  Margaret Thatcher suffered from dementia after several strokes. When she was 83 years old, her daughter Carol Thatcher published the book “In the Goldfish Bowl”. Thatcher published a book, “Swimming in the Goldfish Bowl,” detailing the “Iron Lady’s” condition, saying that as early as 2000 she noticed her mother’s deteriorating health, her memory was failing significantly, and she was experiencing pain and struggle. In 2002, Margaret Thatcher had to give up all public affairs for health reasons and stopped going out to attend speeches and other events.  What is cerebrovascular dementia: Vascular dementia English name: vascular dementiame Abbreviation: VaD is a disease caused by cerebrovascular lesions, with dementia as the main clinical manifestation, previously known as multiple infarct dementia. Dementia can occur after multiple transient ischemic attacks or consecutive acute cerebrovascular accidents, or in individuals, after a severe stroke. Infarct foci are generally small, but the effects can be cumulative. It usually starts in later life and includes multiple cerebral infarct dementia. Dementia caused by cerebrovascular disease is called vascular dementia.  Classification of vascular dementia Common clinical types of vascular dementia Cerebrovascular disease includes cerebral infarction, cerebral hemorrhage, and subarachnoid hemorrhage. The most common cause of cerebrovascular disease is atherosclerosis, and less common are hematologic disease, collagen disease, and vascular malformations. The common clinical types of vascular dementia are: (1) multi-infarct dementia: the most common type. It is dementia due to multiple infarct foci, and the lesions may involve cortical, subcortical and basal ganglia areas. There is often clinical hypertension, atherosclerosis, recurrent cerebrovascular disease, and more or less neurological and psychiatric symptoms left after each attack, which accumulate and eventually become a full-blown, severe mental decline.  (2) Large cerebral infarct dementia: Patients with large cerebral infarcts often die in the acute phase, and the few surviving patients are left with varying degrees of neuropsychiatric abnormalities, including dementia, and loss of work and life skills.  (3) Subcortical atherosclerotic encephalopathy (Binswager’s disease): dementia occurs due to arteriosclerosis and diffuse lesions in the white matter of the brain. Clinical features include decreased intelligence, gait impairment, urinary incontinence, swallowing difficulties, choking and coughing, and slurred speech.  (4) Dementia due to infarction at specific sites: The infarction foci are small but located at sites with important relationship to cognitive function, and cause aphasia, memory deficits, visual impairment, etc.  (5) Hemorrhagic dementia: chronic subdural hematoma, subarachnoid hemorrhage, and cerebral hemorrhage can all produce vascular dementia.  Treatment of cerebrovascular dementia Early diagnosis of cerebrovascular dementia allows measures to be taken to stop the continued progression and deterioration of the disease before symptoms of brain weakness appear. Patients should quit smoking, quit drinking, limit the consumption of animal fats or foods containing high cholesterol, eat more vegetables and fruits, and eat foods containing iodine appropriately to prevent the progress of arteriosclerosis. At the same time, you should insist on physical activities and outdoor activities, ensure sufficient sleep and maintain a good and optimistic mood.  The drugs that have a therapeutic effect on cerebrovascular dementia are those that lower cholesterol, protect and dilate blood vessels, improve cerebral blood circulation, and improve brain cell metabolism. To date, there is no ideal “special drug”. Therefore, it is better to treat the disease than to prevent it.  Since vascular dementia is an irreversible disease and there is no specific drug to treat it, any active measures can only achieve the purpose of delaying the progress of the disease and reducing functional degeneration. The prevention of vascular dementia must start at a young age with the prevention of hypertension, hyperlipidemia and cerebral arterial sclerosis. We must establish a good lifestyle and diet, strengthen exercise, refrain from smoking and alcohol, regulate diet to prevent excessive obesity, and cultivate a cheerful personality; in old age, we must continue to study, strengthen memory training, actively participate in social activities, and maintain an optimistic mood.  For patients with vascular dementia, systematic treatment should be done in the hospital. The main purpose is to improve cerebral blood flow, prevent cerebral infarction and promote cerebral metabolism to stop deterioration and relieve symptoms.  ”Britain has lost a great leader.” The person who gave this comment was the current British Prime Minister David Cameron, while the person who was highly praised was Margaret Thatcher, the first female Prime Minister in British history and the only female Prime Minister so far. Both prime ministers are from the Conservative Party.  The 87-year-old Iron Lady was eventually struck down by a “stroke”, and her misfortune makes us lament that illness does not depend on human will. We should cherish life and guard our health!