Non-steroidal anti-inflammatory drugs, such as ibuprofen, ketoprofen, indomethacin and naproxen, are commonly used for all types of headaches, as well as pain in other areas, and common headaches, such as migraine and tension headaches can be applied. If the patient is due to intracranial organic lesions, such as early brain tumors, headaches may occur and can be applied in milder cases. In severe cases, specific painkillers, such as morphine and pindesine, are usually used. It can also be applied if the patient has a headache due to otitis media, gingivitis, or paranasal sinusitis. Other pain can also be used, such as joint pain as well as low back pain, etc. The main side effects of the drug are gastrointestinal reactions. If the patient has stress ulcers or peptic ulcers, it is generally used with caution or prohibited. If the drug is used for a long time, the kidney function and liver function should be checked regularly.