Acid reflux has no effect on nucleic acid testing. Nucleic acid testing, generally referred to as viral DNA or RNA testing, is one of the more reliable methods of confirming the diagnosis of a viral infection and the results are not affected by a medical condition. By collecting a specimen for viral nucleic acid testing, the presence of a viral infection can be determined. Viruses are one of the most common pathogens that cause infectious diseases, and the clinical manifestations of viral infections are often not specific enough to rely solely on symptoms for diagnosis. If the nucleic acid test is positive, the diagnosis is clear and provides the basis for the next step of treatment. If the nucleic acid test result is abnormal, medical attention and treatment should be sought as soon as possible. Some viruses are highly contagious and require isolation.