Breast nodules that manifest as stabbing pains, similar to pins and needles, are commonly the nodules caused by breast enlargement. The increase in pain is considered to be due to an increase in the size of the local nodule, but there are also certain triggering factors, such as the influence of hormone levels in the body during the premenstrual period, which can manifest as congestion and edema of the breast tissue. A common symptom is pain in the breast that can appear as tingling, and nodules can be affected by adverse external stimuli, such as mood swings or local trauma, or frequent late nights. If necessary, this should be combined with a color ultrasound examination of the breast and regular examination of the breast nodules. If necessary, surgical treatment is also an option, especially if the nodules are gradually increasing in size and the pain is affecting the quality of life. Local anesthesia or epidural anesthesia can be used to remove the lesion, and it is also important to pay attention to the regularity of life, to rest on time, and to avoid adverse stimulation.