In clinical practice, there are two main reasons for the discharge of fleshy tissue during menstruation: First, the discharge of fleshy tissue during menstruation is mainly due to the formation of uterine meconium surrounded by blood and mucus in the vagina, which is a normal phenomenon and does not require treatment. Secondly, the discharge of fleshy tissue during menstruation may be caused by biochemical pregnancy, endometrial polyp, submucosal fibroid or endometrial tumor lesion. In biochemical pregnancy, the endometrium is abnormally thickened, and the embryonic tissue and meconium are exfoliated, which can have fleshy tissue. Endometrial polyps or submucosal fibroids, which are caused by lesions, can be exfoliated with the exfoliated endometrium and can have fleshy tissue changes when discharged. Endometrial neoplastic lesions are localized masses or hyperplastic tissues, which are more brittle and prone to necrosis, and can have fleshy tissue changes when the necrotic tissue is discharged.