Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in orthopedics. NSAIDs are divided into three main groups: monosalicylic acid: represented by aspirin, diphenylamine: represented by paracetamol, and tripropionic acid: represented by ibuprofen. In orthopedic treatment, piroxicam and diclofenac are recommended. Because these drugs have fewer side effects and have a stimulating effect on cartilage metabolism and protein polyribose synthesis. Try to avoid the use of aspirin, salicylic acid, indomethacin and other drugs with high side effects and damaging effects on articular cartilage.