The outcome of the development of high alanine aminotransferase depends on the cause of the high alanine aminotransferase. Common causes can be seen in the following situations, and the developmental outcome varies with different etiologies.1. Physiological causes: High alanine aminotransferase can occur after a late night the day before, strenuous exercise, or during female pregnancy; in this case, the prognosis is generally good. It will return to normal soon after the removal of the causative factors. It can usually be treated without medication. However, it is necessary to review after removing the trigger, and if it returns to normal, there is no problem. However, if it is still elevated, pay attention to check whether there are other pathological causes; 2. Pathological causes: more common ones such as fatty liver, chronic hepatitis B, chronic hepatitis C, autoimmune liver disease, alcoholic liver damage, drug-related liver damage, EBV infection, cytomegalovirus infection, acute cholecystitis, cholangitis, etc. The first four types of liver diseases are chronic liver damage, if not given treatment, the disease can continue to progress and develop ending in liver fibrosis, compensated cirrhosis, decompensated cirrhosis, and liver cancer. Alcoholic liver damage and drug-related liver damage can be normalized in most patients if they can stop drinking and stop using liver-damaging drugs, but if they continue to drink alcohol and take liver-damaging drugs, they can also develop into cirrhosis and liver cancer. EBV infection and cytomegalovirus infection, if the antiviral is effective, liver damage can be improved subsequently. In chronic EBV infections, there are no specific antiviral drugs, and alanine aminotransferase may continue to rise, requiring prolonged liver preservation therapy. In acute cholecystitis and cholangitis, if the infection is fought and the inflammation subsides, alanine aminotransferase will return to normal.