The normal range of alanine aminotransferase is 0-40U/L. If alanine aminotransferase 53U/L is detected, it is mildly elevated, which may be caused by physiological factors and can be taken without medication for a while. If it is caused by pathological factors, such as viral hepatitis, drug-related liver injury, etc., treatment is needed for the cause of the elevated alanine aminotransferase and medication may be required. If the elevation is not obvious, the patient can improve the alanine aminotransferase by paying attention to rest and adjusting the diet structure, so that the alanine aminotransferase can return to normal, usually without medication. Pathological factors: 1, viral hepatitis: such as the existence of hepatitis B, hepatitis C and other viral hepatitis, the patient’s liver inflammatory changes can lead to mildly elevated alanine aminotransferase, such as elevated to 53U/L, while the liver may also exist viral replication, patients need to actively carry out antiviral treatment, taking antiviral drugs, such as acyclovir, after the virus is inhibited, alanine aminotransferase will gradually Restore normal; 2. Drug-related liver injury: clinically some drugs may cause liver injury, such as raw heshouwu, isoniazid, phenobarbital, etc. If the liver is damaged due to the toxic effects of drugs or metabolites, it can also cause mild elevation of alanine aminotransferase, such as elevation to 53 U/L. After stopping taking liver-damaging drugs, the mildly elevated alanine aminotransferase can return to normal; 3. Fatty liver: patients with excessive accumulation of fat cells in the liver, resulting in liver lesions, can be manifested as mildly elevated alanine aminotransferase, such as elevated to 53U/L, patients need to increase exercise, control the diet, alanine aminotransferase can gradually return to normal; 4, biliary system diseases: if patients have gallstones, with cholangitis or cholecystitis, etc., affecting the normal function of the liver, can also appear Mild elevation of alanine aminotransferase, such as elevation to 53 U/L, accompanied by fever and epigastric pain. At this time, it is necessary to take amoxicillin and other antibiotics to treat the primary disease, and if necessary, surgery should be done to remove the stone and release the obstruction. If the treatment is effective, alanine aminotransferase can be gradually reduced. If the patient has elevated alanine aminotransferase, it is recommended to consult a doctor in time to clarify the cause through serological examination, ultrasound and other auxiliary means, and then take appropriate and effective treatment plan according to the doctor’s recommendation for symptomatic treatment. Patients should maintain an optimistic mood and active exercise to enhance physical fitness, which is conducive to disease recovery.