The vague pain in the stomach and intestines during menopause is considered to be caused by gastrointestinal dysfunction, chronic gastritis, gastric ulcer and other diseases during menopause, so it is necessary to clarify the cause of the disease, and according to the cause of the disease, carry out medication, psychological treatment, surgical treatment and so on. 1. Gastrointestinal dysfunction: Gastrointestinal dysfunction can occur during menopause, leading to vague pain in the stomach and intestines. Patients can follow the doctor’s prescription for drug treatment. To treat the symptoms of gastrointestinal pain, patients can take gastrointestinal stimulating drugs, such as domperidone, mosapride, etc.; acid inhibiting drugs, such as pantoprazole, omeprazole, etc.; antacids, such as magnesium aluminum carbonate, aluminum hydroxide gel. Accompanied by symptoms such as menopause, can also take estrogen, estradiol valerate, etc., the specific dosage should be formulated by the doctor according to the condition. Patients can also be counseled psychologically to understand the symptoms of menopause and adjust their mentality so as to better face the disease of menopause. 2. Chronic gastritis: If the patient himself suffers from chronic gastritis, he may also experience vague pain in the stomach and intestines, accompanied by nausea, acid reflux and other symptoms. Need to be treated according to the cause of the disease, the root cause of Hp, commonly used for bismuth quadruple program, proton pump inhibitors (PPI) such as omeprazole, pantoprazole + bismuth, such as bismuth potassium citrate + 2 kinds of antimicrobial drugs, such as clarithromycin, amoxicillin; pro-dynamic drugs, such as domperidone, itopride and so on. 3. Gastric ulcer: If the patient himself suffers from gastric ulcer, stomach pain, loss of appetite and other symptoms can occur. Patients need to maintain a good mood, good habits, acid suppression therapy. The use of proton pump inhibitors such as omeprazole, pantoprazole, gastric mucosal protective agents such as magnesium aluminum carbonate, etc., serious cases need surgical treatment. Menopausal gastrointestinal pain should be timely medical care, identify the cause, and treatment. In addition, the specific use of the above drugs need to be under the guidance of a doctor.