Lung nodule 14mm*17mm visible lobulated pleural depression vacuolar sign is usually the imaging description of lung nodule, and this kind of nodule is mostly high-risk nodule for lung cancer. According to the Chinese Guidelines for Classification, Diagnosis and Treatment of Lung Nodules, the criteria for high-risk nodules and management strategies are as follows: 1. Criteria: solid lung nodules between 8 mm and 15 mm in diameter with a length of ≥15 mm or exhibiting malignant CT signs (lobulation, burr, pleural pulling, air-containing bronchiolar and vesicular signs, and eccentric thick-walled cavities). 2. Management strategy: All high-risk lung cancer nodules should undergo multidisciplinary consultation to decide whether further investigations (including bronchoscopy, enhanced CT, PET-CT, percutaneous lung aspiration biopsy, etc.) are needed to clarify the diagnosis and what treatments should be taken. Surgical treatment is preferred for those who are highly suspected of malignancy and are suitable for surgical treatment. If the physical examination reveals the above manifestations of lung nodules, it is important to pay attention to them and go to a regular hospital for further consultation and treatment in time.