How long to take Epalrestat tablets needs to be determined according to the severity of the disease, such as the condition is mild, after taking a significant improvement, usually need to take one to three months. If the condition is more serious, you need to take more than three months, such as taking the drug for three months when the condition does not change significantly, there is no need to continue to take, you need to change other drugs under the guidance of the doctor. Epalrestat tablets are a kind of medication for the treatment of diabetic neuropathy, the specific time of taking should be determined by the doctor according to the severity of the disease and the efficacy of the drug to the patient, due to the relatively long treatment time of neuropathy, generally need to be taken for at least one to three months in order to determine the efficacy of the drug. Possible adverse reactions to the use of the drug include diarrhea, nausea, vomiting, rash, itching, and elevated bilirubin. It is contraindicated for those who are allergic to the product and the ingredients contained in it. The use of the drug requires attention to the following matters: if an allergic reaction occurs, it is necessary to immediately stop the drug, allergic people, pregnant and lactating women should be cautious. Urine may appear brownish red color after taking the drug. The use of this drug should be under the guidance of a doctor, strictly follow the instructions of the application, to avoid unauthorized increase or decrease in the dosage or discontinuation of the drug triggered by the adverse consequences.