Small blisters on the fingers are painless and itchy, and are mostly considered to be caused by contact dermatitis, eczema, and varicella-zoster virus. According to the different causes of the selection of appropriate drug treatment. 1. Contact dermatitis: Mild contact dermatitis often shows mild edema, erythema or pinpoint-sized dense papules. It can be treated by topical application of mometasone furoate cream and dianabed cream. These drugs have anti-inflammatory, antipruritic, anti-allergic effects, for such diseases can play a relief and improve the purpose. 2. Eczema: Acute eczema or subacute eczema will show symptoms such as red papules, pimples or blisters, scaling or crusting. It can be treated with antihistamines, such as chlorpheniramine maleate tablets and levocetirizine hydrochloride. 3. Varicella-zoster virus: Acute infections caused by varicella-zoster virus usually present as erythema, blisters, papules, and later along the peripheral nerve distribution area, with pain and a burning sensation. It can be treated with neomycin ointment or mupirocin ointment. Small blisters on the fingers without pain or itching may also be caused by other reasons. It is recommended that patients go to the hospital in time, improve the examination to clarify the cause of the disease, and follow the doctor’s instructions to standardize the treatment, so as not to delay the condition.