Kidney stones usually do not cause elevated creatinine, but if the kidney stones are large, leading to chronic obstruction, hydronephrosis and pyuria, which damage the kidney tissues, elevated creatinine can occur. Kidney stones are caused by the formation of stones in the kidneys from some components of the urine, leading to a series of symptoms in patients. Patients may experience back pain, hematuria, nausea, and other symptoms. In general, patients with kidney stones who take active treatment measures have a better prognosis and usually do not damage their kidneys. Therefore, most patients with kidney stones will not have elevated creatinine. However, due to different personal conditions, some patients with severe symptoms of kidney stones may also be complicated with pyelonephritis, renal pus and other infections, which will destroy the kidney tissues. If the stones block the upper urinary tract completely, leading to hydronephrosis, and if the obstruction is not relieved in time, it may lead to kidney failure. In all such cases, a decrease in glomerular filtration rate and an increase in creatinine will occur. Once diagnosed with kidney stones, patients should consult a regular hospital in time and actively cooperate with doctors to take relevant treatment measures to avoid delaying the condition.