When a patient has an acute extensive anterior wall myocardial infarction, it is recommended to start with chewable aspirin, clopidogrel, and resuprastatin, which can provide intensive antiplatelet and intensive lipid-lowering effects. At the same time, nitroglycerin or isosorbide nitrate can be administered intravenously, and a coronary angiogram should be prepared at the same time as these preparations. If the patient cannot undergo coronary intervention, coronary artery bypass grafting is an option. If the patient does not want to undergo thrombolysis and cannot undergo coronary intervention due to financial difficulties, it is recommended to opt for conservative drug treatment, which will result in a very poor prognosis and a high risk of death within hours or even a week. Therefore, patients are advised to choose coronary angiography as much as possible and take drugs such as Bolivar, also known as clopidogrel for about a year, and aspirin can preferably be taken orally for a long time for life.