Patient: Since childhood, I have had to undergo surgery and did not cure. How should I remove A: Hello! A mole is a nest or mass of mole cells that proliferate in the skin. Because mole cells can secrete melanin particles, resulting in its surface appears black or brown, black nevus or pigmented nevus is thus named. Some nevi are innate, while others are a product of birth, mostly appearing after the age of 2 years. Most moles grow slowly or remain unchanged for many years and have no uncomfortable symptoms. With age, nevus cells gradually move from the superficial layer of the skin into the dermis, and their number gradually increases, generally reaching a peak at puberty. There are three types of moles: moles with cells distributed in the dermis are called intradermal moles, which appear as papilloma-like bumps, and almost all hemispherical and tipped moles are intradermal moles, which are stable and the safest; moles with cells distributed between the dermis and the epidermis are called junctional moles, most of which are flat and have the greatest risk of becoming malignant tumors, and are therefore the most dangerous; moles with both of these properties are called Mixed nevi, which are slightly higher than the skin, have a certain tendency to become malignant after long-term irritation. There are two kinds of treatment methods for moles, surgical and non-surgical. Surgical treatment is suitable for nevus with larger area or malignant signs, and the cut down nevus should be examined to determine its benign and malignant degree and to understand the condition of the surgical cut edge. Non-surgical treatments, such as laser, electrocautery, freezing, chemical cautery, etc., are only suitable for moles with a diameter of less than 5 mm, superficial, clear diagnosis and long-term stability. The choice of method for mole removal should follow the doctor’s opinion. Repeated photothermal and other effects may increase the chance of malignant changes in moles and must be used with caution. Some patients with pigmented nevi that show no obvious signs of malignancy may be followed up for a long time.